Tc-43/novel_myosin_modulator_designs
Novel Myosin Motor Modulators — GA-II Designed Ligand–Receptor Complexes Why this target matters. Direct myosin modulation is the first therapeutic strategy to target cardiac contractility at the motor protein itself, a mechanism validated clinically by mavacamten's approval in hypertrophic cardiomyopathy. 22 small molecules generated de novo by the Technetium TC-43.ai engine (GA-II), conditioned on the allosteric modulator site of the myosin motor domain. Each molecule was… See the full description on the dataset page: https://huggingface.co/datasets/Tc-43/novel_myosin_modulator_designs.
| Author / organization | Tc-43 |
|---|---|
| License (as declared) | cc-by-4.0 |
| Downloads | 370 (as reported by Hugging Face) |
| Likes | 0 |
| Created | 30 September 2025 |
| Last updated at source | 16 September 2026 |
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