Tc-43/KRAS_CyclophilinA_MolecularGlue
KRAS–Cyclophilin A Molecular Glues — Ligand–Receptor Complexes Why this target matters. RAS is mutated in roughly a quarter of all human cancers, and the cyclophilin A tri-complex mechanism reaches KRAS in its active, GTP-bound state — the form conventional inhibitors cannot engage. 40 small molecules generated de novo by the Technetium TC-43.ai engine (GA-II), conditioned on the KRAS · Cyclophilin A ternary interface, so that one molecule bridges both proteins. Each molecule… See the full description on the dataset page: https://huggingface.co/datasets/Tc-43/KRAS_CyclophilinA_MolecularGlue.
| Author / organization | Tc-43 |
|---|---|
| License (as declared) | cc-by-4.0 |
| Downloads | 769 (as reported by Hugging Face) |
| Likes | 0 |
| Created | 30 September 2025 |
| Last updated at source | 16 September 2026 |
Popularity, last 3 days
769 now (-15 since 2026-10-16). Counts as reported by the source, snapshotted daily by Silytics.
More from Tc-43
Silytics shows public metadata from Hugging Face and links to the original. Information may be incomplete or out of date. Last refreshed 18 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.