Tc-43/ACE2-B0AT1
ACE2–B0AT1 Ligand Designs — Ligand–Receptor Complexes Why this target matters. B0AT1 (SLC6A19) is a rare transporter target with direct human genetic validation — people who lack it (Hartnup disorder) are largely healthy — making it an unusually de-risked oral route to lowering blood phenylalanine in phenylketonuria. 38 small molecules generated de novo by the Technetium TC-43.ai engine (GA-II), conditioned on the ACE2 · B0AT1 (SLC6A19) complex. Each molecule was constructed… See the full description on the dataset page: https://huggingface.co/datasets/Tc-43/ACE2-B0AT1.
| Author / organization | Tc-43 |
|---|---|
| License (as declared) | cc-by-4.0 |
| Downloads | 708 (as reported by Hugging Face) |
| Likes | 0 |
| Created | 7 October 2025 |
| Last updated at source | 16 September 2026 |
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