Tc-43/VHL_NonProline_Binder_Designs_9GIO
VHL Non-Proline Binder Designs (9GIO) 279 small molecules generated de novo by the Technetium TC-43.ai engine (GA-II), conditioned on the VHL substrate-recognition pocket of the VHL–ElonginC–ElonginB (VCB) complex (PDB 9GIO), with the field's usual hydroxyproline anchor withheld during generation. Each molecule was constructed against this pocket rather than selected from a compound library — docking (AutoDock Vina) came afterwards, to place and score the generated molecules in… See the full description on the dataset page: https://huggingface.co/datasets/Tc-43/VHL_NonProline_Binder_Designs_9G
| Author / organization | Tc-43 |
|---|---|
| License (as declared) | cc-by-4.0 |
| Downloads | 263 (as reported by Hugging Face) |
| Likes | 0 |
| Created | 3 September 2026 |
| Last updated at source | 16 September 2026 |
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