Tc-43/SMARCA2_VHL_MolecularGlue_Designs_6HAY
SMARCA2–VHL Molecular Glue Designs (PDB 6HAY) 884 small molecules generated de novo by the Technetium TC-43.ai engine (GA-II), conditioned on the SMARCA2 bromodomain–VHL interface of the ternary complex 6HAY (2.24 Å), so that one molecule spans both partners. Each molecule was constructed against this pocket rather than selected from a compound library — docking (AutoDock Vina) came afterwards, to place and score the generated molecules in the site. Each is supplied as a… See the full description on the dataset page: https://huggingface.co/datasets/Tc-43/SMARCA2_VHL_MolecularGlue_Designs_6HAY.
| Author / organization | Tc-43 |
|---|---|
| License (as declared) | cc-by-4.0 |
| Downloads | 244 (as reported by Hugging Face) |
| Likes | 0 |
| Created | 5 September 2026 |
| Last updated at source | 16 September 2026 |
Popularity, last 9 days
244 now (-9 since 2026-10-16). Counts as reported by the source, snapshotted daily by Silytics.
More from Tc-43
Silytics shows public metadata from Hugging Face and links to the original. Information may be incomplete or out of date. Last refreshed 24 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.