Tc-43/CRBN_Binders
Cereblon (CRBN) Binders — Ligand–Receptor Complexes Why this target matters. Cereblon is the most clinically validated E3 ligase handle in medicine — the direct target of thalidomide, lenalidomide and pomalidomide, and the recruiting engine behind most molecular glues and PROTACs now in the clinic. 221 small molecules generated de novo by the Technetium TC-43.ai engine (GA-II), conditioned on the cereblon thalidomide-binding domain — the classic tri-tryptophan glutarimide… See the full description on the dataset page: https://huggingface.co/datasets/Tc-43/CRBN_Binders.
| Author / organization | Tc-43 |
|---|---|
| License (as declared) | cc-by-4.0 |
| Downloads | 177 (as reported by Hugging Face) |
| Likes | 0 |
| Created | 15 January 2026 |
| Last updated at source | 16 September 2026 |
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