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Paper · arXiv

The Value of System 1 Models in Medicine

Many clinical decisions are a choice among a few fixed options, taken quickly and in large numbers. Such decisions also need an uncertainty estimate to know when to defer to a clinician. Generative language models answer slowly in free text and state their confidence poorly. In contrast, System 1 models answer zero-shot with a probability for each answer. However, their performance across clinical tasks is unknown. Four System 1 models, two proprietary and two with open weights, were evaluated zero-shot on 86 public tasks from 14 clinical domains in 20 languages, spanning examination questions and medical imaging. Tasks were assigned to six capability tiers before analysis. The primary ou...

AuthorsXiufeng Yang, Konstantinos Vrettos, Zeineb Ben Chaaben et al.
Primary categorycs.LG
Published22 October 2026
Last updated at source22 October 2026
cs.LG
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