BatchBench: Benchmarking AI Robustness to Batch Effects and Domain Shift in Biomedical Images - A JUMP Cell Painting Leaderboard
Despite recent advances, current AI systems remain highly susceptible to domain shifts, particularly in biomedical imaging, where images are usually acquired under substantially different experimental conditions. Although recent domain adaptation methods have made substantial progress, significant performance gaps under domain shift persist. To measure progress in this regard, we introduce BatchBench, a leaderboard that evaluates and compares the robustness of AI systems on biomedical images from unseen experimental batches and data sources. BatchBench is built on JUMP-CP, one of the largest publicly available biomedical imaging datasets. Generated using the Cell Painting assay, JUMP-CP e...
| Authors | Sonja Topf, Ana Sanchez-Fernandez, Günter Klambauer |
|---|---|
| Primary category | cs.LG |
| Published | 21 October 2026 |
| Last updated at source | 21 October 2026 |
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