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Paper · arXiv

Manifold-Informed Neural Networks for Low-Label ECG Electrolyte Inference

Physics-informed neural networks (PINNs) supervise on the residual of a known differential operator. Many high-stakes inference problems admit no such operator: clinical signals, behavioral measurements, materials properties. We introduce the Manifold-Informed Neural Network (MINN), a PINN-parallel paradigm that replaces the physics operator residual with a manifold operator residual: a discrete Poisson equation $\mathbf{L}_G \mathbf{H} = s_φ(\mathbf{x}, \mathbf{m})$ on a $k$-nearest-neighbor graph in the learned latent space, with a learned, task-aware source. The construction is a structural parallel to PINNs (squared operator residual plus label data, in place of operator residual plus...

AuthorsJuntang Wang, Hao Wu, Yihan Wang et al.
Primary categorycs.LG
Published20 October 2026
Last updated at source20 October 2026
cs.LG
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