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Paper · arXiv

CODA: Cohort- and Drift-aware Foundation Model for Multimodal Clinical Reasoning

Recent advances in multimodal foundation models have demonstrated strong performance across diverse clinical tasks. However, existing approaches predominantly operate at the individual sample level and fail to model the interplay between population-level cohort patterns and patient-specific variation that underlie real-world clinical reasoning. In practice, clinicians routinely reason through patient cohorts sharing similar demographic, physiological, or pathological characteristics, while accounting for patient-specific deviations from the group prototype. Motivated by this gap, we propose CODA, a cohort- and drift-aware foundation model for multimodal clinical reasoning. CODA explicitly...

AuthorsChangshuo Liu, Jiaqi Zhu, Wenqiao Zhang et al.
Primary categorycs.AI
Published19 October 2026
Last updated at source19 October 2026
cs.AIcs.LG
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