Concurrent two-scale topology optimization of printable bone scaffolds via rectified-flow generation and exact latent-space refinement
Bone scaffolds must reconcile a macroscale mechanical response with microscale geometric feasibility, yet conventional approaches to their design restrict attainable constitutive properties. This work presents a concurrent two-scale topology optimization framework; a conditional rectified flow generates periodic lattice microstructures, which are then refined in latent space by exact finite-element homogenization sensitivities. The resulting unit-cell geometries and their spatial assignments are jointly optimized under mechanical and feature-size constraints. In a distal rabbit femur benchmark, all eight flow-started refinements produce printable cells with maximum relative errors under 1...
| Authors | Reza T Batley, Sourav Saha |
|---|---|
| Primary category | physics.comp-ph |
| Published | 18 October 2026 |
| Last updated at source | 18 October 2026 |
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