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Paper · arXiv

Trust the Edge, Doubt the Arrow: Auditing Validation Signals for Text-Mined Clinical Causal Knowledge Graphs

Clinical causal retrieval-augmented generation systems increasingly use knowledge graphs (KGs) mined from notes, yet extracted assertions remain candidates that require audit for patient-level EHR support and direction. We construct a directed candidate graph from 328,839 MIMIC-IV discharge summaries using LLM extraction and UMLS normalization, and evaluate three signals against SemMedDB: within-admission co-occurrence lift, cross-admission diagnosis-coding temporal precedence, and literature corroboration. Lift filters unsupported co-mentions and provides useful EHR support, but not causal proof. Coding order is a weak direction signal: among the 686 candidates where it commits, it reach...

AuthorsSu Lan, Shicheng Zhou, Yiqi Wang et al.
Primary categorycs.AI
Published17 October 2026
Last updated at source17 October 2026
cs.AI
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