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Paper · arXiv

Learning from the Right Regions: Class-Conditioned Explanation Guidance for Medical Imaging

Deep neural networks can achieve strong predictive performance in medical imaging while relying on regions unrelated to the predicted finding. Explanation-guided learning can address this problem, but multi-label classification introduces a key challenge: multiple abnormalities may coexist in an image, requiring each prediction to align with its corresponding spatial evidence. We propose a class-conditioned explanation-guided learning framework that constructs a separate explanation for each positive class and penalizes evidence outside its class-specific annotated regions. We instantiate the framework using Gradient-weighted Class Activation Mapping (Grad-CAM) and evaluate it on 14 abnor...

AuthorsZubair Faruqui, Rahul Dubey
Primary categorycs.CV
Published17 October 2026
Last updated at source17 October 2026
cs.CVcs.LG
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