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Paper · arXiv

International Multi-Centre Validation of Unsupervised Domain Adaptation for Precise Discrimination between Normal and Abnormal Retinal Development

Arrested retinal development can cause childhood visual impairment, but grading optical coherence tomography scans is difficult to standardise across devices and centres. We developed and evaluated an unsupervised domain adaptation model to classify normal and abnormal retinal development across different OCT systems. This retrospective multicentre study used OCT scans from five centres in four countries and the UK Biobank. Data covered four OCT devices, including table mounted and handheld systems. A ResNet50 based Domain Adversarial Neural Network was trained using labelled images from a source device and unlabelled images from a target device. We evaluated six source to target pairings...

AuthorsZhanhan Tu, Nikhil Reddy, Helen J. Kuht et al.
Primary categorycs.CV
Published15 October 2026
Last updated at source15 October 2026
cs.CVcs.LG
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