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Paper · arXiv

ReproBAIT: Can coding agents build their own biological AI tools?

Large language models are increasingly competent at leveraging scientific knowledge and existing computational tools to execute complex workflows. At present, little information exists on their ability to reconstruct tools when given limited descriptions of such tools. We introduce an evaluation titled ReproBAIT (Reproducing Biological AI Tools), which measures the ability of coding agents to design, implement, and train biological AI tools taken from published research across a range of information access conditions. The coding agent is securely sandboxed without internet access and receives training data, a fixed time and compute budget, and limited information about the tool to replica...

AuthorsShiv Muthupandiyan, Tolga H. Dur, Mac Walker et al.
Primary categorycs.AI
Published14 October 2026
Last updated at source14 October 2026
cs.AIcs.CYcs.LG
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