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Paper · arXiv

LabOPBench: A Multimodal Benchmark for Evidence-Grounded Laboratory Decision Making

Laboratory experiments involve more than following predefined protocols; they require adaptive decision-making as the experimental state changes. Existing scientific benchmarks rarely assess such evidence-based decisions in laboratory settings. Here we present LabOPBench, a multimodal benchmark of 756 expert-authored, independently reviewed questions in organic synthesis and materials science. Each item pairs laboratory evidence with procedural context and an open-ended judgment, evaluated using a question-specific scoring rubric. Eight multimodal models obtain overall normalized scores of 28.8-45.8%, leaving substantial room for improvement. On a controlled 100-question subset, the stron...

AuthorsJingyuan Li, Yujie Liu, Yijie Dai et al.
Primary categorycs.AI
Published14 October 2026
Last updated at source14 October 2026
cs.AI
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