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Paper · arXiv

Learning When to Trust Medical Knowledge: Regression-Safe Routing for Clinical Reasoning

Clinical reasoning LLMs need external medical knowledge, but retrieved evidence and reasoning chains can be outdated, poisoned, or hallucinated. Harmful knowledge can cause regression: changing a correct answer into an incorrect one. We construct a medical knowledge-poisoning benchmark covering retrieved evidence and reasoning chains, with seven attack families filtered by a three-judge "subtle-but-wrong" vote and paired clean exams that separate poisoning effects from question difficulty. No fixed knowledge-use strategy is robust across these settings: strong RAG methods trade robustness to poisoned evidence against accuracy when evidence is useful. We formulate knowledge use as per-inst...

AuthorsHui Zhang, Yujia Zeng, Yuhao Xin
Primary categorycs.AI
Published14 October 2026
Last updated at source14 October 2026
cs.AI
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