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Paper · arXiv

Diagnosing Low-Confidence Patient Profiles via Localized Harmful Covariate Shift Detection

Before deploying clinical prediction models, their reliability must be assessed to ensure safe use. Errors may arise from distribution shifts between training and deployment or from heterogeneous performance where the model systematically underperforms for certain patient subgroups. Yet most post-hoc diagnostic methods evaluate reliability only at the population level, checking whether the deployment data resemble the training data and whether the model performs well on average, without accounting for heterogeneity that may cause some patients to be disproportionately affected. We propose a unified diagnostic pipeline that combines both perspectives. MED3pa first discovers interpretable l...

AuthorsOlivier Lefebvre, Hakima Laribi, Dan Poenaru et al.
Primary categorycs.LG
Published13 October 2026
Last updated at source13 October 2026
cs.LGcs.AI
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