Task-evoked eye movements as candidate digital biomarkers of depression severity in adolescents and young adults
Objective digital measures of depression severity could complement conventional symptom assessments and facilitate more timely clinical evaluation. Here, we investigated whether task-evoked eye movements provide interpretable behavioral markers of depression severity in adolescents and young adults. In this single-center, cross-sectional study, 155 participants aged 14--20 years completed emotional-spatial free-viewing and memory-guided recall tasks and were stratified by 17-item Hamilton Depression Rating Scale scores. We examined 19 prespecified eye-movement features across six task-informed domains using covariate-adjusted ordinal-trend models. Greater depression severity was associate...
| Authors | Youxiang Sun, Yujie Nie, Zhuoru Wu et al. |
|---|---|
| Primary category | eess.SP |
| Published | 13 October 2026 |
| Last updated at source | 13 October 2026 |
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