When Participant Disjoint Validation Is Not Enough to Establish Generalization in Parkinson's Gait Classification
Participant-disjoint cross-validation prevents direct participant overlap, but it may still produce optimistic estimates when acquisition site and diagnosis are structurally dependent. We examined Parkinson's disease classification using 159 pressure-walkway summary features from 133 WearGait-PD participants, including 65 participants with Parkinson's disease and 68 controls. The cohort was non-factorial: two sites contained only one diagnostic group, whereas VA-Seattle was the only site containing both groups. In repeated participant-level nested cross-validation, site alone achieved an area under the receiver operating characteristic curve (AUC) of 0.955 plus or minus 0.003, exceeding t...
| Authors | Md. Sifat, Sania Akter, Akif Islam et al. |
|---|---|
| Primary category | cs.LG |
| Published | 12 October 2026 |
| Last updated at source | 12 October 2026 |
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