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Paper · arXiv

Personalized Physiological-Model-Based Neural Network for Glucose Forecasting in Type 1 Diabetes

Accurate, physiologically consistent glucose forecasts could help people with type 1 diabetes respond to impending excursions. We applied our physiological-model-based neural network (PMB--NN) framework to glucose forecasting. A temporal convolutional network (TCN) used 180 min of history, constrained during training by a personalized four-parameter physiological model. The main PMB--NN combined forecast and neural--physiological agreement losses; a three-term variant additionally fitted physiological predictions to measured glucose. Data comprised 6--8 weeks of continuous glucose monitoring, pump, and meal records from 25 AZT1D participants. Person-specific models used chronological 70/1...

AuthorsYaowen Zhang, Shuhao Que, Ying Wang
Primary categoryphysics.med-ph
Published11 October 2026
Last updated at source11 October 2026
physics.med-phcs.LG
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