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Paper · arXiv

Siam-ALS: An Explainable Siamese Deep Learning Framework for Early ALS Detection Using EEG and Eye-Tracking Signals

Amyotrophic lateral sclerosis (ALS) diagnosis remains challenging due to heterogeneous symptoms and reliance on clinical assessment, underscoring the need for objective, data-driven approaches that leverage patient-generated physiological signals. We propose Siam-ALS, an explainable Siamese deep learning framework that jointly models synchronized electroencephalography (EEG) and eye-tracking (ET) signals. EEG captures ALS-related changes in brain activity, while ET provides information about oculomotor control, allowing the model to learn complementary patterns associated with ALS. The framework employs two modality-specific encoders: a convolutional EEG encoder that captures spatiotempor...

AuthorsAbdur Rahman, A. A. M. Muzahid, Istiak Ahmed et al.
Primary categorycs.LG
Published11 October 2026
Last updated at source11 October 2026
cs.LGcs.AI
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