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Paper · arXiv

Expert-level detection of low-voltage intervals in EEG as a robust biomarker of neonatal encephalopathy

Background: Discontinuity in neonatal EEG is a critical marker of brain dysfunction but can be difficult to quantify visually. Inter-burst intervals (IBIs) are a key characteristic of discontinuity, yet their definition does not easily translate to AI detection. Objectives: To introduce low-voltage intervals (LVIs), defined exclusively by amplitude and duration, as a context-independent alternative to IBIs, develop an AI detection method for LVIs, and assess their clinical utility as a marker of brain injury. Methods: We developed a ConvNeXt model to detect LVIs and compared its performance with existing methods. We then tested the clinical relevance of detected LVIs across four applicati...

AuthorsJohn M. O'Toole, Sean R. Mathieson, Aurel Luca et al.
Primary categorycs.LG
Published8 October 2026
Last updated at source8 October 2026
cs.LGeess.SPphysics.med-ph
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