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Paper · arXiv

GlucoPRISM: Protocol-Supervised Pretraining for Cross-Cohort Glucose Transfer

Continuous glucose monitoring (CGM) foundation models encode each day as one vector that mixes who the person is, what happened that day and how the sensor measured it, so measurement differences travel with the representation into new cohorts. We ask whether pretraining can place the measurement component that harms transfer in known coordinates, so that deployment drops them with a fixed projection and no target data. GlucoPRISM supervises a GlucoFM backbone with response contracts, rules for how each part of the representation should change when only the day or only the sensor changes: a 64-dimensional Trait band should change with neither, a 48-dimensional State band only across days,...

AuthorsAdinath Madhavrao Dukre, Abdullah Mohammad, Yifan Lu et al.
Primary categorycs.LG
Published8 October 2026
Last updated at source8 October 2026
cs.LG
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