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Paper · arXiv

OA-MAP: Evidence-Grounded Multi-Agent Multimodal Framework for Interpretable Knee Osteoarthritis Progression

Knee osteoarthritis (KOA) progression prediction can support patient monitoring, requiring the integration of multimodal data and multidomain expertise. Moreover, isolated risk estimates provide limited insight underlying a prediction. To automate the progression assessment workflow and reduce manual effort while providing interpretable findings and supporting evidence, we present OA-MAP, an autonomous multi-agent framework for evidence-grounded assessment of structural and pain progression in KOA. The system incorporates modality-specific agents including MRI, X-ray, and clinical agents, together with a coordinator agent. This framework can autonomously recruit specialist agents, select ...

AuthorsSixu Chen, Mingrui Yang, Qiang Guan et al.
Primary categorycs.AI
Published8 October 2026
Last updated at source8 October 2026
cs.AIcs.MA
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