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Paper · arXiv

SepsisLens: Structure-Preserving Sequence Modelling for Decomposable Early Sepsis Warning

Early sepsis warning from ICU records can be cast as a structure-preserving prediction problem. A model needs to detect deterioration from irregular measurements while keeping each alert connected to the physiological signals that support it. Many temporal models fuse clinical variables into a patient-level representation, supporting scalar risk prediction but weakening the structure needed for clinical decomposition. We present SepsisLens, which preserves variable-indexed temporal states until risk composition. Observation-aware representations encode each variable's dynamics and measurement history, while a shared temporal encoder models each trajectory without collapsing the variable a...

AuthorsYikun Ou, Wei Li
Primary categorycs.LG
Published6 October 2026
Last updated at source6 October 2026
cs.LG
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