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Paper · arXiv

Patch-based Querying Identifies Structures of Interest in Electron Microscopy

Volume electron microscopy (vEM) has emerged as an essential sensing technique in biomedical research, allowing the three-dimensional imaging of biological cells and tissues at nanometer-scale resolution. The ability to generate extensive datasets has reached the limitations of downstream analysis processes, which depend significantly on the intervention of human experts for preprocessing and annotation. We propose an efficient and reliable patch-based retrieval framework based on self-supervised learning of local image descriptors to locate self-similar structures in vEM datasets. Given a few manual annotations of a given cellular structure, our method can retrieve similar structures acr...

AuthorsNiels Vyncke, Nicolas Nadisic, Yvan Saeys et al.
Primary categorycs.CV
Published5 October 2026
Last updated at source5 October 2026
cs.CV
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