Riemannian Shape Analysis of the Corpus Callosum in Kendall Space: Aging and Alzheimer's Disease
The corpus callosum (CC) is a major white-matter structure and a well-established marker of brain aging, but most studies quantify it using scalar summaries that discard its boundary geometry. We present a Riemannian shape-space framework \cite{fletcher2013geodesic-regression} for analyzing age-related morphological change in the midsagittal CC, applied to the OASIS-1 cohort. Each contour is represented by $128$ landmarks and embedded into Kendall shape space, where translation, rotation, and scale are removed. We derive a multivariate geodesic regression with exact Riemannian gradients and use the fitted age-velocity field to localize age-related deformation to five anatomical sub-region...
| Authors | Olakunle S. Abawonse, Fatou Fall |
|---|---|
| Primary category | cs.CV |
| Published | 4 October 2026 |
| Last updated at source | 9 October 2026 |
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