CellSplat4D: PSF-Aware 4D Gaussian Splatting for Sparse Robotic Live-Cell Imaging
A robotic microscope watching living cells cannot afford to look as often as it would like. Every volume it acquires costs photons the specimen does not get back, and time owed to other wells. What such a platform exists to produce is a record of individual cells through time: which cell is which from one volume to the next, and which cell divided into which two. Sampling sparsely breaks that record exactly where it matters, and the fault lies in the acquisition schedule rather than in the analysis software. We fill the gaps by reconstructing them, fitting a 4D Gaussian model to whatever volumes the hardware could afford. The model is a cloud of light-emitting blobs, each carrying a posit...
| Authors | Yingda Tao, Guoyu Lu |
|---|---|
| Primary category | cs.CV |
| Published | 3 October 2026 |
| Last updated at source | 3 October 2026 |
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