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Paper · arXiv

Hyperparameter selection for equation learning with biologically-informed neural networks

Biologically-informed neural networks (BINNs) have emerged as a flexible subclass of physics-informed neural networks (PINNs) for learning terms in partial differential equations from data. BINNs are particularly suited for biological systems, where the governing equations are highly nonlinear and only partially known a priori, and where data observations are often sparse, noisy, and incomplete. However, applying BINNs effectively in practice depends critically on hyperparameter selection, which remains a central challenge in equation-learning frameworks. Hyperparameters are often chosen heuristically and only cursorily documented, which limits the reproducibility of results and the trans...

AuthorsWilliam Lavery, Jodie A. Cochrane, John T. Nardini et al.
Primary categorycs.LG
Published2 October 2026
Last updated at source2 October 2026
cs.LG
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