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Paper · arXiv

Large language models exhibit unreliable updating of clinical judgment as patient evidence evolves

Large language models (LLMs) are increasingly explored for clinical reasoning, but whether they appropriately revise judgments as patient evidence evolves remains unclear. We evaluated longitudinal belief updating using matched intensive-care trajectories from electronic health records. Across diverse LLMs, conditioning on a preceding judgment more often increased than reduced prediction error when estimates changed, replicated for a second endpoint. Controlled interventions revealed two failure modes. First, with preceding assessment fixed, models responded more strongly to worsening than matched improving respiratory evidence; this asymmetry persisted after headroom normalization at mod...

AuthorsMin Zeng, Rui Zhang
Primary categorycs.AI
Published2 October 2026
Last updated at source2 October 2026
cs.AIcs.CL
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