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Paper · arXiv

Evaluating Biomedical Reranking for LLM-Based Question Answering over Longitudinal Clinical Notes

Patient-specific clinical question answering requires locating the right evidence within long, heterogeneous longitudinal clinical records in which relevant facts may be scattered across encounters, repeated in copied-forward notes, or expressed using different clinical terminology. We evaluated whether biomedical reranking can improve evidence selection and downstream answer quality in a locally deployed retrieval-augmented generation pipeline for longitudinal clinical notes. The pipeline combines PubMedBERT dense retrieval, BM25 lexical retrieval, weighted reciprocal-rank fusion, and MedCPT cross-encoder reranking. Across 1,000 open- and closed-ended question-answer pairs from a cohort ...

AuthorsMaryam Shahbaz Ali, Laura B. Strachan, Caitlin Sherman et al.
Primary categorycs.CL
Published1 October 2026
Last updated at source1 October 2026
cs.CLcs.ET
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