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Paper · arXiv

PrivMeSA: Privacy-Aware Self-Evolving Multi-Agent System for Medicine via Local-Remote LLM Collaboration

Clinical large language model (LLM) agents deployed locally can consult more capable remote models, but doing so risks exposing patient information. Privacy-conscious delegation places disclosure decisions with a local agent, yet removing explicit identifiers is insufficient: quasi-identifiers can accumulate across multi-turn consultations and repeated patient visits to enable re-identification. We introduce PrivMeSA, a privacy-aware self-evolving multi-agent system that learns to control disclosure and retains remote expertise for local reuse. A local agent manages each encounter and consults remote specialists that may request additional information. Reinforcement learning balances task...

AuthorsDannong Wang, Yuran Zhang, Bian Sun et al.
Primary categorycs.AI
Published29 September 2026
Last updated at source29 September 2026
cs.AI
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