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Paper · arXiv

Reduce, Then Encode: Multiscale Volumetric Reduction for 2D Foundation Models in Brain MRI

Pretrained 2D foundation models offer a practical alternative to dedicated 3D pretraining for brain structural magnetic resonance imaging (sMRI), but their use on volumetric data requires bridging the mismatch between a 2D encoder and a 3D volume input. Existing methods typically encode slices independently and integrate their features afterwards. We introduce Multiscale Volumetric Reduction (MVR), a reduce-then-encode approach that compresses each anatomical view from (D) slices into (M << D) complementary 2D components before foundation-model encoding. MVR combines an uncentered-PCA base component derived from the original through-plane intensities with residual detail components constr...

AuthorsDexuan Ding, Yuankai Qi, Bogong Wang et al.
Primary categorycs.CV
Published28 September 2026
Last updated at source28 September 2026
cs.CV
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