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Paper · arXiv

Role-Guided MOE for Encoder-Level Pathology Representation Learning in WSI Classification

Whole slide image classification is a fundamental task in computational pathology, where patch representation quality directly affects downstream aggregation and slide-level discriminability. Pathology foundation models are widely adopted as frozen feature extractors for WSI classification; however, their fixed encoders may produce representations insufficiently adapted to target-specific tissue patterns and discriminative cues. Fine-tuning can improve target adaptation, but introduces a trade-off between pathology-specific representation capacity and adaptation efficiency, particularly in data-scarce settings. To address this, we propose a pathology role-guided mixture-of-experts feed-fo...

AuthorsXinyu Ma, Xing Yang, Hongtao Jin et al.
Primary categorycs.CV
Published28 September 2026
Last updated at source28 September 2026
cs.CV
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