BIABench: Evaluating AI agents on real-world bioimage analysis tasks

Artificial-intelligence (AI) agents hold promise for automating bioimage analysis, yet no benchmark evaluates whether they can carry out real-world analyses end to end. Such analyses are hard for agents because 2D images, 3D volumes and time-lapse sequences are often too large to read as context, so an agent must choose and run an analysis through code, specialized software and rendered views. Published studies make this capability testable, because each pairs raw images with a peer-reviewed result. We introduce BIABench, a benchmark of 16 tasks reconstructed from published biological studies that retain their scientific questions, imaging data and ground truth. The tasks span eleven anal...

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