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Paper · arXiv

Contamination, Prior, or Evidence? Decomposing and Training Evidence Use in Whole-Slide Vision-Language Models

Pathology vision-language models (VLMs) are conventionally evaluated by accuracy, but accuracy alone does not measure evidence use: it may conflate dataset contamination, prior knowledge, and image evidence. In a motivating study of lymph-node metastasis prediction, we found that most public pathology VLMs showed minimal differences when changing from feeding the models with whole-slide images, an annotated lesion, or no image at all. To better understand the specific features leveraged by these models, this paper presents two contributions aimed at disentangling these factors. First, we present CleanSlide, a TCGA-based VQA benchmark designed to eliminate image- and question-side contamin...

AuthorsWenhao Zhang, Zhongliang Zhou, Shiyuan Zhang et al.
Primary categorycs.CV
Published26 September 2026
Last updated at source26 September 2026
cs.CVcs.LG
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