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Paper · arXiv

BioDyad: Synchronize Biomedical Discovery and Machine Learning Engineering

Agentic biomedical machine learning (ML) draws on complementary advances in biomedical evidence acquisition and executable program search. Existing systems connect aspects of these capabilities, but coordinating them throughout program search remains challenging. New evidence must guide candidate construction, execution outcomes must inform subsequent discovery and reuse, and validation demands must fit the search budget. We introduce BioDyad, which couples biomedical discovery and ML engineering through two hierarchies within Monte Carlo graph search. Its scientific hierarchy combines prior biomedical guidance with iterative discovery, then links biomedical plans to execution outcomes in...

AuthorsXingbo Du, Fadli Aulawi Al Ghiffari, Leonard Song et al.
Primary categorycs.AI
Published25 September 2026
Last updated at source25 September 2026
cs.AI
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