Federated Targeted Maximum Likelihood Estimation
The evidence behind a scientific or operational decision is often held by hospitals, banks, or registries that cannot pool individual observations. Cross-silo federated learning moves computation to the data and exchanges agreed summaries. Targeted maximum likelihood estimation (TMLE) refines a flexible initial fit, yielding plug-in estimators that respect the model and support efficient inference. TMLE itself, however, has remained a fully centralized procedure. To fill this gap, our paper introduces the first federated TMLE algorithm. We federate targeting itself, for an arbitrary target, loss, and fluctuation family, through two complementary frameworks. FedTMLE-G aggregates local grad...
| Authors | Diyang Li, Fei Wang, Kyra Gan |
|---|---|
| Primary category | cs.LG |
| Published | 24 September 2026 |
| Last updated at source | 24 September 2026 |
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