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Paper · arXiv

False-science induction in autonomous scientific discovery

Closed-loop discovery systems increasingly execute experiments and update decisions autonomously, turning record integrity into part of the experimental apparatus. We show that false-science induction arises when legitimate physical objects and measurements are paired incorrectly, driving neural surrogates to faithfully learn record-induced associations that do not correspond to the true object-outcome relationship while marginal data distributions remain unchanged. Across green fluorescent protein fitness and materials band-gap prediction loops, coherent paired misbinding systematically redirects experimental budgets toward low-performing basins, whereas same-volume random swaps have neg...

AuthorsHanbing Liang, Fujun Liu
Primary categorycs.LG
Published20 August 2026
Last updated at source20 August 2026
cs.LGcs.AIphysics.comp-ph
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