Syndrome, Synergy, and Safety: Structured Reasoning and Knowledge-Driven Alignment for TCM Prescription Generation
Applying large language models to Traditional Chinese Medicine (TCM) prescription generation reveals three clinically critical gaps: models produce end-to-end mappings without auditable reasoning following the li-fa-fang-yao paradigm (SR Gap), treat each encounter in isolation without follow-up adjustment via sui zheng jia jian (LA Gap), and fail to enforce absolute contraindication rules such as Shi Ba Fan (SC Gap). We propose a progressive four-stage framework (SFT $\to$ PG-CoT $\to$ Dynamic $\to$ K-RL) that addresses each gap: PG-CoT constrains CoT distillation under the li-fa-fang-yao paradigm to produce auditable diagnostic chains, Dynamic SFT models patient trajectories with explici...
| Authors | Zheng Chen, ZhiCheng Du, Haoxuan Li et al. |
|---|---|
| Primary category | cs.CL |
| Published | 22 September 2026 |
| Last updated at source | 22 September 2026 |
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