Decoupling Disease, Covariates, and Individual Variability: A Unified Disentanglement Framework for Medical Image Classification
Accurately isolating disease-related features from confounding covariates (e.g., age, gender, site) and individual variations remains a fundamental challenge in medical image classification. Traditional regression-based approaches may ignore non-linear relations between image features and true covariates. To overcome this issue, we present a generalized Medical Imaging Disentanglement Learning (MedIDL) framework. MedIDL maps image features into three mutually orthogonal latent spaces through specialized disentanglement heads: a disease classification head guided by a supervised loss, a covariate-alignment head constrained by cross-subject similarity matching, and a Gaussian head absorbing...
| Authors | Shengjie Zhang, Jinglin Zhang, Zhuangzhuang Jiang et al. |
|---|---|
| Primary category | cs.CV |
| Published | 22 September 2026 |
| Last updated at source | 22 September 2026 |
Silytics shows public metadata from arXiv and links to the original. Information may be incomplete or out of date. Last refreshed 17 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.