Preoperative Prediction of Microvascular Invasion in Hepatocellular Carcinoma by Integrating Multimodal Ultrasound and Clinical Data: A Multicenter Study
Background: Microvascular invasion (MVI) predicts recurrence and survival in hepatocellular carcinoma (HCC) but requires postoperative histopathology for diagnosis. We developed and validated a model integrating multimodal ultrasound and clinical data for preoperative MVI prediction. Methods: This multicenter study included 489 patients with HCC from eight centers. All patients had B-mode ultrasound (BUS), color Doppler flow imaging (CDFI), dynamic contrast-enhanced ultrasound (DCE-US), and clinical information. Data from seven centers (n = 421) were used for model development with five-fold cross-validation; data from the remaining center (n = 68) formed an independent external validatio...
| Authors | Jun Cheng, Yuanyuan Kong, Qing Huang et al. |
|---|---|
| Primary category | cs.CV |
| Published | 21 September 2026 |
| Last updated at source | 21 September 2026 |
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