Lesion-Gated Hybrid Synthesis for Virtual Contrast-Enhanced Breast MRI: A MAMA-SYNTH Challenge Solution

Purpose: Contrast-enhanced breast MRI depends on intravenous gadolinium-based contrast agents, motivating methods that synthesise post-contrast appearance from pre-contrast images alone. The MAMA-SYNTH Challenge (MICCAI 2026 Deep-Breath Workshop) evaluates such synthesis across four metric groups: image fidelity, tumour region of interest, downstream classification, and downstream segmentation. The four group ranks are averaged, so optimising a single objective is insufficient. Materials and Methods: We developed a lesion-gated hybrid synthesis pipeline. A lesion probability map, estimated from the pre-contrast slice alone by an ensemble of pre-contrast-only segmentation networks, spatial...

<iframe src="https://silytics.si/embed/item/77f1d671-7177-4ddd-8e2a-8aaa257487ee" width="420" height="190" style="border:0" loading="lazy" title="Silytics entry"></iframe>

Silytics shows public metadata from arXiv and links to the original. Information may be incomplete or out of date. Last refreshed 17 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.