Intervention Granularity Matters: Coherent Treatment Bundles in Counterfactual Simulation with Clinical World Models
Counterfactual simulation with a clinical world model means fixing a patient's history, changing the treatment, and reading off the predicted response. Doing so requires deciding what counts as one intervention. In clinical settings, interventions are documented as bundles: a co-occurrence audit of 945,707 patient-hours from MIMIC-IV shows groups of components, such as every parameter of a dialysis circuit, that never appear apart, so an edit that changes one component on its own describes an hour that never occurs in the data. We hypothesize that the granularity at which an intervention is edited changes how a world model responds, and test this with Clin-JEPA, a latent world model of pa...
| Authors | Fangzhou Wang, Yixuan Yang, Camilla Balzarotti et al. |
|---|---|
| Primary category | cs.LG |
| Published | 18 September 2026 |
| Last updated at source | 18 September 2026 |
Silytics shows public metadata from arXiv and links to the original. Information may be incomplete or out of date. Last refreshed 17 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.