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Paper · arXiv

TrialAtlas: Multi-Agent Research Organization for Clinical Trial Design and Optimization

Nearly 90% of drugs entering clinical development ultimately fail, despite billions of dollars in investment. Pharmaceutical companies therefore rely on clinical development planning (CDP) and probability of technical and regulatory success assessment to anticipate development risks, yet these decisions remain labor-intensive and subjective, requiring experts across clinical science, statistics, regulatory affairs, and competitive intelligence to jointly acquire, synthesize, and reason over heterogeneous evidence. Here, we introduce TrialAtlas, a memory-augmented multi-agent research organization for CDP that mirrors this collaborative process by coordinating specialized agents for litera...

AuthorsJiacheng Lin, Zifeng Wang, Zheng Chen et al.
Primary categorycs.CL
Published18 September 2026
Last updated at source18 September 2026
cs.CL
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