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Paper · arXiv

Reliability-Centered Evaluation of Sparse Longitudinal CT Lesion-Size Forecasting with Conformal Interval Calibration and Gompertz-Inspired Regularization

Sparse longitudinal CT follow-up limits lesion-size forecasting when only a few prior observations are available. We constructed a five-visit DLT-derived same-lesion trajectory benchmark from DeepLesion and Deep Lesion Tracker (DLT), yielding 205 trajectories from 129 patients. We compared an exploratory conventional sparse-to-final analysis with a primary fixed visit-index horizon design predicting the common log change from T3 to T4 while progressively adding earlier observations, evaluating predictive accuracy, uncertainty reliability, post-hoc conformal interval calibration, subgroup performance, and Gompertz-inspired trajectory regularization. The evaluated methods showed partially o...

AuthorsLingfei Kong
Primary categorycs.LG
Published18 September 2026
Last updated at source18 September 2026
cs.LGq-bio.QMstat.ME
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