Ischemic Stroke Segmentation and Net Water Uptake Quantification on Multicenter Non-Contrast CT Using Supervised Target-Domain Adaptation
Objectives: Quantitative assessment of infarct hypodensity on non-contrast computed tomography (NCCT), including net water uptake (NWU), requires manual or semi-manual lesion delineation, often guided by CT perfusion or diffusion-weighted MRI, limiting clinical applicability. Automated segmentation on NCCT could enable efficient biomarker extraction such as NWU but remains challenging across heterogeneous multicenter data. This study aimed to develop and externally test a domain-aware deep learning framework for ischemic stroke segmentation on NCCT and assess its suitability for NWU quantification. Materials & Methods: In this retrospective multicenter study of 801 patients from four data...
| Authors | Linus Britt, Maximilian Nielsen, Susan Klapproth et al. |
|---|---|
| Primary category | cs.CV |
| Published | 17 September 2026 |
| Last updated at source | 18 September 2026 |
Silytics shows public metadata from arXiv and links to the original. Information may be incomplete or out of date. Last refreshed 17 October 2026. Licenses and terms of the original apply to the work itself. Not financial, legal or professional advice.