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Paper · arXiv

BioPhys-Bridge: A Benchmark for Interdisciplinary Scientific Reasoning in Physics-Grounded Biological Research

Language models face unique challenges in analyzing interdisciplinary scientific research literature. In biophysics research, faithful answers require grounding observed data in source evidence, interpreting it through a quantitative physics model, and linking it to a biological mechanism. To address this challenge, we introduce BioPhys-Bridge, a novel benchmark dataset for evidence-grounded scientific reasoning over biophysical literature. Each case contains evidence blocks, stable evidence IDs, quantitative values, units, equations, assumptions, mechanisms, and next decisions as grounding targets for question answering (QA) and retrieval-augmented generation (RAG). The initial release c...

AuthorsQingyang Xu
Primary categorycs.AI
Published15 September 2026
Last updated at source15 September 2026
cs.AIq-bio.QM
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