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Paper · arXiv

MUMINS: Metadata-conditioned Uncertainty-aware Medical Image Next-state Synthesis

Forecasting anatomical changes such as tumor growth and neurodegeneration is a challenging generative vision task. Morphological evolution is subtle relative to static anatomy, highly patient-specific, and inherently stochastic. Existing methods struggle with several issues: deterministic networks ignore biological stochasticity, while standard diffusion models require computationally prohibitive multi-pass sampling to quantify uncertainty. We propose MUMINS (Metadata-conditioned Uncertainty-aware Medical Image Next-state Synthesis), an efficient diffusion framework that jointly diffuses a baseline scan and its follow-up residual, summed to synthesize the follow-up scan, while concurrentl...

AuthorsAnna Oliveras, Roger Marí, Rafael Redondo et al.
Primary categorycs.CV
Published15 September 2026
Last updated at source15 September 2026
cs.CVcs.AI
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